HORDB

ID: hor006527
Uniprot ID: P08163(124-159)
Protein name: Glycoprotein
Gene name: NA
Organism: Bufo japonicus (Japanese toad)
Family: Vasopressin/oxytocin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Bufo (genus), Bufonidae (family), Hyloidea (superfamily), Neobatrachia (suborder), Anura (order), Batrachia (superorder), Amphibia (class), Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005185 neurohypophyseal hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: VTPEQNMTQMDGSASDLLLRLMHMANRQQQSKHQFY
Length: 36(124-159)
Propeptide: TAPVPACFLCLLALSSACYIQNCPRGGKRSYPDTAVRQCIPCGPGNRGNCFGPNICCGEDLGCYVGTPETLRCVEETYLPSPCEAGGKPCSSGGRCAAPGVCCSDDTCVVDSSCLDEDSERRRVTPEQNMTQMDGSASDLLLRLMHMANRQQQSKHQFY
Signal peptide: TAPVPACFLCLLALSSA
Modification: NA
Glycosylation: T6 N-linked (GlcNAc...) asparagine
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006527_AF2.pdb

hor006527_ESM.pdb

Mass:	486028	Formula:	C178H285N55O57S4
Absent amino acids:	CIW	Common amino acids:	Q
pI:	7.71	Basic residues:	5
Polar residues:	9	Hydrophobic residues:	8
Hydrophobicity:	-87.5	Boman Index:	-9030
Half-Life:	100 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	56.94
Instability Index:	7455.28	Extinction Coefficient cystines:	1490
Absorbance 280nm:	42.57

PubMed ID: 3033676
Title: Cloning and sequence analysis of cDNAs for neurohypophysial hormones vasotocin and mesotocin for the hypothalamus of toad, Bufo japonicus.